Case Studies

Case Studies

Click through our range of case studies below to find out how Aspherix® and CFDEM®coupling is applied to effectively support simulations in various industries.

Modelling of Hot Melting Extrusion

Modelling of Hot Melting Extrusion

Twin-screw extruders (TSEs) are widely used for processing polymers, chemicals and foodstuff.

Development of a 1D-3D model for polymer extrusion in TSE (collaboration with Novartis*)

The 3D part consists of DEM simulations of representative volume elements (RVEs)

The 1D part is a low-order model bridging the solution between the RVEs

*https://www.aiche.org/academy/conferences/aiche-annual-meeting/2022/proceeding/paper/45f-3d-1d-modelling-twin-screw-extruders

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Mower Deck Optimization

Mower Deck Optimization

The goal of this case study with Aspherix® and CFDEM®coupling was the optimization of a mower deck with respect to ths cut quality. Since the design contains blades with intersection trajectories it was not possible to use sliding meshes. An immersed boundary approach, especially designed for mower deck applications was used. The simulation results matched experimental data and it was possible to compare different geometry setups and boundary conditions and optimize them.

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Tablet Press Feeding Segregation

Tablet Press Feeding Segregation

Simulation of commercial scale tablet press feed system with a coupled CFD-DEM model.

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Rotary Tablet Press

Rotary Tablet Press

DEM simulations of rotary tablet press in collaboration with Alkermes Inc.*


Effect of paddle and turret velocities (from 20 to 80 RPM) on:

  1. Powder residence time and travel distance distributions
  2. Shear work done on the powder
  3. Mass of the dosage
  4. Variability of API concentration in the dosage


*Li, Zihao, et al. “Particle Scale Insights into a KG-Pharma RoTab Tablet Press Feed-Frame System Using the Discrete Element Method (DEM) Modeling.” Processes 11.1 (2023): 119.

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White Paper: Effect of the Shape of Slurry Particles on Their Infiltration Behaviour

Effect of the shape of slurry particles on their infiltration behaviour

This white paper by Jianyuan Liu and Kevin J. Hanley from the University of Edinburgh summarizes the results on a study on the effect of the shape of slurry particles in their infiltration behaviour.

White Paper: Numerical investigation of backward erosion piping

Numerical investigation of backward erosion piping

This publication by Hannah Kaiser and Professor Jürgen Grabe describes the numerical investigation of backward erosion piping with Aspherix® and CFDEM®coupling.

DOI: https://doi.org/10.53243/NUMGE2023-107

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